Prep: Bring a large pot of water to a boil and cook lasagna noodles according to the package directions (to al dente). Drain, rinse noodles under cool water to stop the cooking process, and set aside.
Brown Meat: In a large skillet over medium-high heat, melt butter. Add in the minced garlic and sauté for 1 minute, stirring often. Next, add the ground beef to the skillet and cook it until it browns. Break it up with a wooden spoon or potato masher as it cooks. Drain fat, if needed.
Add Veggies: To the meat, add carrot, celery, and onion. Cook for 5 minutes until veggies soften a bit.
Finish the Sauce: Add the pasta sauce, water (or beef broth), Italian seasoning, garlic powder, onion powder, parsley, salt, and pepper. Give everything a big stir and bring to a boil. Then, reduce heat to low and simmer for 15-20 minutes.
Mix: While the sauce is simmering, in a medium mixing bowl, combine ricotta cheese, egg, 1/2 cup Parmesan cheese, 1/2 cup shredded mozzarella cheese, and chopped parsley. Mix until well-combined.
Assemble: Preheat oven to 375°F. Spray a 9x13 baking dish (or similar) with cooking spray.Spread a thin layer of the sauce (meat mixture) on the bottom of the baking dish. Place a layer of pasta noodles (5 noodles) over the sauce.Then, dollop on half of the ricotta mixture. With a spoon, gently spread the ricotta mixture in an even layer.Sprinkle on half of the mozzarella cheese (1 1/2 cups) and half of the Parmesan cheese (1/2 cup) on top of the ricotta. Repeat the layers again, starting with the noodles. Remember: Noodles, Sauce, Ricotta, finish with Parmesan & Mozzarella. Bake: Cover the baking dish with aluminum foil (spray the foil with a little cooking spray so the cheese doesn't stick!) and bake in preheated oven for 35-45 minutes. Remove foil and continue to bake 15 minutes more or until lasagna is hot, bubbly, and the cheese begins to turn golden brown. Note: this cooking time may vary depending on your oven. Cool: Let the lasagna cool for 10-15 minutes before cutting it into 2-inch squares and serving. The longer it cools, the easier it will be to cut it into clean squares.
Garnish (optional): Garnish lasagna with red pepper flakes, fresh basil or parsley, and more grated fresh Parmesan or Parmigiano Reggiano!